SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2

Volume: 382, Issue: 1, Pages: 98 - 109
Published: Oct 1, 2013
Abstract
Previously we demonstrated that BMP signaling is required for endogenous digit tip regeneration, and that treatment with BMP-2 or -7 induces a regenerative response following amputation at regeneration-incompetent levels (Yu et al., 2010, 2012). Both endogenous regeneration and BMP-induced regeneration are associated with the transient formation of a blastema, however the formation of a regeneration blastema in mammals is poorly understood. In...
Paper Details
Title
SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2
Published Date
Oct 1, 2013
Volume
382
Issue
1
Pages
98 - 109
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