Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters
Abstract
Circadian rhythms and sleep are two separate but intimately related processes. Circadian rhythms are generated through the precisely controlled, cyclic expression of a number of genes designated clock genes. Genetic variability in these genes has been associated with a number of phenotypic differences in circadian as well as sleep parameters, both in mouse models and in humans. Diurnal preferences as determined by the selfreported Horne-Ostberg...
Paper Details
Title
Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters
Published Date
Dec 1, 2008
Journal
Volume
87
Issue
5
Pages
513 - 519
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