Determination of PON1 Gene Polymorphisms in Iranian Individuals with High LDL/HDL Ratios

Elevated LDL/HDL ratio is an important risk factor for predicting atherosclerosis. Paraoxonase-1 protects LDLs from oxidative modifications and has a protective effect against atherosclerosis. Two common polymorphisms, Q192R and L55M, in PON1 gene can affect PON1 levels and function. The aim of this study was to evaluate the frequency PON1 polymorphisms in individuals with high and normal LDL/HDL ratios. To evaluate Q192R and L55M polymorphisms...