Lymphoid nodular hyperplasia and cow's milk hypersensitivity in children with chronic constipation

Objective To investigate the incidence of cow's milk allergy as evidenced by milk challenge and the findings of endoscopic and immunohistochemical examinations in children with chronic and refractory constipation. Study design Thirty-five study subjects (mean age, 8.3 ± 3.3 years; range, 3-15 years; 17 girls) and 15 control subjects (mean age, 11.7 ± 3.2 years; range, 2-15 years; 9 girls) were studied by colonoscopy and a 4-week cow's milk...