Comparison of different depletion strategies for improved resolution in proteomic analysis of human serum samples.

Volume: 5, Issue: 1, Pages: 307 - 317
Published: Jan 1, 2005
Abstract
Serum proteins may often serve as indicators of disease and is a rich source for biomarker discovery. However, the large dynamic range of proteins in serum makes the analysis very challenging because high-abundant proteins tend to mask those of lower abundance. A prefractionation step, such as depletion of a few high-abundant proteins before protein profiling, can assist in the discovery and detection of less abundant proteins that may prove to...
Paper Details
Title
Comparison of different depletion strategies for improved resolution in proteomic analysis of human serum samples.
Published Date
Jan 1, 2005
Journal
Volume
5
Issue
1
Pages
307 - 317
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