Green biosynthesis and characterization of fibrin functionalized iron oxide nanoparticles with MRI sensitivity and increased cellular internalization

Developing novel contrast agents for efficient MRI sensitivity is very essential for early diagnosis of cancer. In the present work, we have prepared novel, eco-friendly, non-toxic iron oxide nanoparticles (IONPs) as efficient MRI contrast agents. Earth abundant magnetite sand was used for the preparation of IONPs using acid leaching method. Further, co-precipitation method was used to obtain fibrin functionalized iron nanoparticles (F-IONPs)....