Original paper

On-line derivatization for continuous and automatic monitoring of brain extracellular glutamate levels in anesthetized rats: a microdialysis study

Volume: 734, Issue: 1, Pages: 1 - 6
Published: Oct 1, 1999
Abstract
Glutamate is an important excitatory amino acid in central nervous system. We developed a method for in vivo, continuous and automatic monitoring of brain extracellular glutamate, as well as other amino acids in anesthetized rat. This method involves the use of microdialysis perfusion technique and a high-performance liquid chromatography system equipped with a fluorescence detector. The microdialysate (perfused at a flow-rate of 1 μl/min) was...
Paper Details
Title
On-line derivatization for continuous and automatic monitoring of brain extracellular glutamate levels in anesthetized rats: a microdialysis study
Published Date
Oct 1, 1999
Volume
734
Issue
1
Pages
1 - 6
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