TIRAP C539T polymorphism contributes to tuberculosis susceptibility: Evidence from a meta-analysis

Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP), an important adaptor protein downstream of the Toll-like receptor (TLR) 2 and 4 pathways, is highly involved in the activation and coordination of the anti-mycobacterial immune response. We performed a meta-analysis to assess the association between TIRAP C539T polymorphism and tuberculosis (TB) risk. A systematic literature search for relevant studies up to February 27, 2014...