Original paper
NMDA-dependent superoxide production and neurotoxicity
Abstract
NEURONAL injury resulting from acute brain insults and some neurodegenerative diseases implicates N-methyl-D-aspartate (NMDA) glutamate receptors1–4. The fact that antioxidants reduce some types of brain damage suggests that oxygen radicals may have a role5–7. It has been shown that mutations in Cu/Zn-superoxide dismutase (SOD), an enzyme catalysing superoxide (O·-2) detoxification in the cell, are linked to a familial form of amyotrophic...
Paper Details
Title
NMDA-dependent superoxide production and neurotoxicity
Published Date
Aug 1, 1993
Journal
Volume
364
Issue
6437
Pages
535 - 537
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Notes
History