The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression
Abstract
The importance of anticancer stem cell research for breast cancer lies in the possibility of providing new approaches for an improved understanding of anticancer activity and cancer treatment. In this study, we demonstrated that the preclinical therapeutic efficacy of combining the multikinase inhibitor sorafenib with radiation was more effective in hypoxia-exposed breast cancer stem cells. We assessed cell viability and Annexin V to evaluate...
Paper Details
Title
The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression
Published Date
Jan 8, 2013
Journal
Volume
29
Issue
3
Pages
917 - 924
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