Original paper
A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity
Abstract
Bacteriophages (or phages) are the most abundant biological entities on earth, and are estimated to outnumber their bacterial prey by tenfold. The constant threat of phage predation has led to the evolution of a broad range of bacterial immunity mechanisms that in turn result in the evolution of diverse phage immune evasion strategies, leading to a dynamic co-evolutionary arms race. Although bacterial innate immune mechanisms against phage...
Paper Details
Title
A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity
Published Date
Feb 1, 2013
Journal
Volume
494
Issue
7438
Pages
489 - 491
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Notes
History