The Actomyosin Contractile Ring Regulates Septation during Fission Yeast Cytokinesis

In fungi and metazoans, cytokinesis involves constriction of a contractile actomyosin ring. The role of the ring remains unclear: it is unknown if it sets the constriction rate or has some other function. We combined mathematical modelling and quantitative image analysis of experimental septum measurements to study the interaction between the constricting ring and septation, the growth of new cell wall in the wake of the constricting ring. We...