Synthesis and antibacterial evaluation of a series of oligorhamnoside derivatives

A series of novel oligorhamnoside derivatives (1–10) and naturally occurring cleistrioside-5 were synthesized and evaluated for their in vitro antibacterial activities. Among them, dirhamnoside derivative 7 and cleistrioside-5 displayed similar antibacterial profiles and exhibited moderate to good inhibitory activities on bacterial growth against a panel of Gram-positive bacteria (MICs ⩽ 4–32 μg/mL). The results revealed that these two compounds...