Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/HER2-negative breast cancer
Abstract
Determining the indications for adjuvant chemotherapy (CT) in patients with hormone receptor (HR)-positive/HER2-negative breast cancer are difficult. The transcription factors GATA-binding protein 3 (GATA-3) and Forkhead-box protein A1 (FOXA1) are crucial for the hormone responsive phenotype of breast cancer. This study evaluated whether the expression of GATA-3 and FOXA1 is a prognostic and predictive marker of outcomes in patients with...
Paper Details
Title
Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/HER2-negative breast cancer
Published Date
Jan 11, 2014
Journal
Volume
22
Issue
5
Pages
520 - 528
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