Hydrogen–Deuterium Exchange Mass Spectrometry Reveals the Interaction of Fenna–Matthews–Olson Protein and Chlorosome CsmA Protein

In green-sulfur bacterial photosynthesis, excitation energy absorbed by a peripheral antenna structure known as the chlorosome is sequentially transferred through a baseplate protein to the Fenna-Matthews-Olson (FMO) antenna protein and into the reaction center, which is embedded in the cytoplasmic membrane. The molecular details of the optimized photosystem architecture required for efficient energy transfer are only partially understood. We...