Match!

Weight Lifting and Aortic Dissection: More Evidence for a Connection

Published on Jan 1, 2007in The Cardiology1.561
· DOI :10.1159/000094530
Ioannis Hatzaras5
Estimated H-index: 5
(Yale University),
Maryann Tranquilli21
Estimated H-index: 21
(Yale University)
+ 3 AuthorsJohn A. Elefteriades55
Estimated H-index: 55
(Yale University)
Abstract
Background/Aims: In 2003, we reported on a small number of patients in whom acute aortic dissection appeared to be causally related to intense weight lifting. If additional cases co
  • References (5)
  • Citations (112)
📖 Papers frequently viewed together
1,070 Citations
200351.27JAMA
49 Citations
56 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References5
Newest
#1George J. KoulliasH-Index: 14
#2Raj Modak (Yale University)H-Index: 3
Last. John A. ElefteriadesH-Index: 55
view all 6 authors...
Objective The human ascending aorta becomes markedly prone to rupture and dissection at a diameter of 6 cm. The mechanical substrate for this malignant behavior is unknown. This investigation applied engineering analysis to human ascending aortic aneurysms and compared their structural characteristics with those of normal aortas. Methods We measured the mechanical characteristics of the aorta by direct epiaortic echocardiography at the time of surgery in 33 patients with ascending aortic aneurys...
110 CitationsSource
31 CitationsSource
#2Ioannis HatzarasH-Index: 5
Last. Paul G. BarashH-Index: 35
view all 8 authors...
49 CitationsSource
#1David L.S Morales (Yale University)H-Index: 2
#2Jacquelyn A. Quin (Yale University)H-Index: 4
Last. John A. Elefteriades (Yale University)H-Index: 55
view all 6 authors...
Abstract Background . Aortic fenestration is used clinically to treat organ ischemia in acute descending aortic dissection. However, fenestration has not been studied experimentally. This study does so using an animal model. Methods . Descending aortic dissection was created in six dogs, with subsequent fenestration of the infrarenal aorta. Blood flow (femoral, cephalic, and renal), blood pressure (femoral and carotid), and aortic distensibility were measured at baseline, after dissection, and a...
21 CitationsSource
#1Christian de Virgilio (UCLA Medical Center)H-Index: 28
#2Ronald J. Nelson (UCLA Medical Center)H-Index: 13
Last. John M. Robertson (UCLA Medical Center)H-Index: 17
view all 7 authors...
Abstract We report 4 cases of ascending aortic dissection in patients with long histories of weight lifting. In 2 of the patients, the initial symptoms of dissection developed while they were lifting weights. Two patients had a history of hypertension and 2 had previously used anabolic steroids. All 4 were successfully treated surgically. Histopathology showed aortic medial changes in all 4. We believe that the hemodynamic stresses of weight lifting, namely, a rapid increase in systemic arterial...
34 CitationsSource
Cited By112
Newest
#1Jun An (Yanbian University)
#2Abdelsalam M. Elhenawy (Al-Azhar University)
Acute aortic dissection is uncommon, but can turn into a fatal disease if not managed quickly. A 49-year-old male fighter pilot presented to us after sudden excruciating chest pain during a flight at the moment of an acute spiral down action. A contrast-enhanced computed tomography angiography showed Stanford type A aortic dissection that required surgical ascending aorta and hemiarch replacement with uneventful postoperative recovery and 10-year follow-up. Here, we presented the first report of...
Source
#1Barry A. FranklinH-Index: 55
#2Paul D. ThompsonH-Index: 87
Last. Thijs M.H. EijsvogelsH-Index: 18
view all 10 authors...
Epidemiological and biological plausibility studies support a cause-and-effect relationship between increased levels of physical activity or cardiorespiratory fitness and reduced coronary heart disease events. These data, plus the well-documented anti-aging effects of exercise, have likely contributed to the escalating numbers of adults who have embraced the notion that "more exercise is better." As a result, worldwide participation in endurance training, competitive long distance endurance even...
1 CitationsSource
Source
#1Rohan Bhandari (Cleveland Clinic)
#2Rajani D. Aatre (UM: University of Michigan)H-Index: 1
Last. Yogendra Kanthi (UM: University of Michigan)H-Index: 7
view all 3 authors...
Aortic aneurysms were the primary cause of nearly 10,000 deaths in 2014 according to data from the Centers for Disease Control and may involve segments of the thoracic or abdominal aorta. Thoracic ...
Source
#1Sharon Kay (Kolling Institute of Medical Research)
#2Benjamin M. Moore (USYD: University of Sydney)H-Index: 5
Last. David S. Celermajer (USYD: University of Sydney)H-Index: 88
view all 8 authors...
Background Prompted by a cluster of observations concerning ascending aortic pathology in elite rugby players, we assessed over 150 asymptomatic predominantly retired players with echocardiography, aiming to document the prevalence and severity of ascending aortic dilatation and/or anterior aortic effacement, both ‘risk factors’ for potentially catastrophic aortic complications. Methods Rugby players (at least 5 years of high level competitive rugby) were classified as elite (national, state or ...
Source
#1Carlijn G.E. Thijssen (EUR: Erasmus University Rotterdam)
#2Lidia R. Bons (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Jolien W. Roos-Hesselink (EUR: Erasmus University Rotterdam)H-Index: 50
view all 8 authors...
ABSTRACTIntroduction: Current guidelines recommend patients with thoracic aortic disease (TAD) including inherited aortopathies to avoid heavy exercise. However, evidence supporting the negative ad...
Source
#1Davide Carino (Yale University)H-Index: 3
#2Mohammad A. Zafar (Yale University)H-Index: 6
Last. John A. Elefteriades (Yale University)H-Index: 55
view all 5 authors...
Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Their high tissue distribution and broad-spectrum antibacterial coverage make their use very attractive in numerous infectious diseases. Although generally well tolerated, FQs have been associated with different adverse effects including dysglycemia and arrhythmias. FQs have been also associated with a series of adverse effects related to collagen degradation, such as Achilles tendon rupture and retinal detach...
1 CitationsSource
#1Elie Salameh (AUB: American University of Beirut)
#2Charbel Saade (AUB: American University of Beirut)H-Index: 7
Last. Ghanem F. Oweis (AUB: American University of Beirut)H-Index: 9
view all 3 authors...
Purpose In a curved vessel such as the aortic arch, the velocity profile closer to the aortic root is normally skewed towards the inner curvature wall, while further downstream along the curve, the velocity profile becomes skewed towards the outer wall. In an aortic dissection (AD) disease, blood velocities in the true lumen (TL) and false lumen (FL) are hypothesized to depend on the proximity of the entry tear to the root of aortic arch. Faster velocity in the FL can lead to higher hemodynamic ...
Source
#1Matthew R. Bersi (Yale University)H-Index: 12
#2Chiara Bellini (Yale University)H-Index: 10
Last. Stéphane Avril (University of Lyon)H-Index: 29
view all 4 authors...
We recently developed an approach to characterize local nonlinear, anisotropic mechanical properties of murine arteries by combining biaxial extension–distension testing, panoramic digital image correlation, and an inverse method based on the principle of virtual power. This experimental–computational approach was illustrated for the normal murine abdominal aorta assuming uniform wall thickness. Here, however, we extend our prior approach by adding an optical coherence tomography (OCT) imaging s...
6 CitationsSource
#1Alan C. Braverman (WashU: Washington University in St. Louis)H-Index: 25
Thoracic aortic aneurysm disease is an important cause of morbidity and mortality. Recognizing the specific disorder responsible for the condition informs management, including screening of first-degree relatives, imaging strategies, and determining the timing of prophylactic surgery or endovascular repair. Pharmacologic therapy typically involves beta adrenergic blocking agents, which slow the heart rate and lower blood pressure. Hemodynamic benefits of beta blockers may lessen stress on the ao...
Source