A randomized, double‐blind, placebo‐controlled multicenter trial evaluating topical zinc oxide for acute open wounds following pilonidal disease excision

The purpose of this randomized, double‐blind, placebo‐controlled multicenter trial was to compare topical zinc oxide with placebo mesh on secondary healing pilonidal wounds. Sixty‐four (53 men) consecutive patients, aged 17–60 years, were centrally randomized to either treatment with 3% zinc oxide ( n =33) or placebo ( n =31) by concealed allocation. Patients were followed with strict recording of beneficial and harmful effects including masked...