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mTOR and cancer: many loops in one pathway
Abstract
The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division that responds to a variety of stimuli, including nutrient, energy, and growth factors. In the last years, a significant number of pieces have been added to the puzzle of how mTOR coordinates and executes its functions. Extensive research on mTOR has also uncovered a complex network of regulatory loops that impact the therapeutic approaches aimed at...
Paper Details
Title
mTOR and cancer: many loops in one pathway
Published Date
Apr 1, 2010
Volume
22
Issue
2
Pages
169 - 176
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