Three-dimensional pattern recognition: An approach to automated interpretation of electron density maps of proteins
Abstract
A procedure is outlined for reducing the high resolution electron density map of a protein to a set of connected thin lines which follow the density. The side chain representations are removed from this skeleton leaving primarily main chain, disulfide bridges and very strong hydrogen bonds. Crystallographic and local operators are used to separate one protein molecule from the neighboring chains in the crystal. Provisional α-carbon positions...
Paper Details
Title
Three-dimensional pattern recognition: An approach to automated interpretation of electron density maps of proteins
Published Date
Jan 1, 1974
Journal
Volume
82
Issue
3
Pages
279 - 301
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