Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN.

Volume: 289, Issue: 1, Pages: 198 - 204
Published: Nov 23, 2001
Abstract
The superimposition of male sex organs (penis and vas deferens) in a female gastropod, called imposex, is widely attributed to the exposure to tributyltin (TBT) compounds, used world-wide in antifouling paints for ships. It has been hypothesized that the TBT-induced imposex is mediated by an increasing androgen level relative to the estrogen level, namely a decreased conversion of androgens to estrogens (i.e., aromatization). In the present...
Paper Details
Title
Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN.
Published Date
Nov 23, 2001
Volume
289
Issue
1
Pages
198 - 204
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