Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
Abstract
Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent. Despite chemotherapy, the global tuberculosis epidemic has intensified because of HIV co-infection, the lack of an effective vaccine and the emergence of multi-drug-resistant bacteria. Alternative host-directed strategies could be exploited to improve treatment efficacy and outcome, contain drug-resistant strains and reduce...
Paper Details
Title
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
Published Date
Jun 25, 2014
Journal
Volume
511
Issue
7507
Pages
99 - 103
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