Depressive spectrum diagnoses

Published on Mar 1, 2000in Comprehensive Psychiatry 2.13
· DOI :10.1016/S0010-440X(00)80007-3
Jules Angst77
Estimated H-index: 77
Robert Sellar1
Estimated H-index: 1
Kathleen R. Merikangas100
Estimated H-index: 100
There has been widespread debate about the validity of the contemporary diagnostic classification system of depression. The major goal of this study is to examine the prognostic significance of each of the major subtypes of depression using data from 5 interviews of a 15-year prospective community-based cohort study. The stability of the following diagnostic subtypes across the duration of the study was examined: major depressive disorder (MDD), dysthymia, recurrent brief depression (RBD), and minor depression. The results show that there was little stability for the specific subtypes of depression among those who continued to manifest depression during the follow-up period; 51% of those with MDD and 44% of those with RBD met criteria for another subtype of depression. When stability was observed, the same subtype often occurred in combination with the development of another subtype. Among individuals with a single subtype, severity was greatest among those with dysthymia, whereas individuals with combined subtypes had greater severity than those with a single subtype. The lack of longitudinal stability of the diagnostic subtypes of depression suggests that depression is better expressed as a spectrum rather than a set of discrete subtypes.
  • References (38)
  • Citations (119)
Published on Apr 1, 1994in The Journal of Clinical Psychiatry 4.25
Lewis L. Judd52
Estimated H-index: 52
Mark Hyman Rapaport47
Estimated H-index: 47
+ 1 AuthorsJ. L. Brown1
Estimated H-index: 1
Secondary analyses in a subsample (N=9160) of the National Institute of Mental Health Epidemiologic Catchment Area Program data base revealed that 19.6% of the general population reported one or more depressive symptoms in the previous month. One-year prevalence of two or more depressive symptoms in the general population was 11.8%, a prevalence figure exceeding the 9.5% 1-year prevalence for all the DSM-III mood disorders combined. We have labeled this potential clinical condition as subsyndrom...
314 Citations
Published on Jul 1, 1997in American Journal of Psychiatry 13.40
Robert D. Levitan42
Estimated H-index: 42
Alain Lesage40
Estimated H-index: 40
+ 2 AuthorsSidney H. Kennedy72
Estimated H-index: 72
Objective: Most research on depression with reversed neurovegetative features (hypersomnia, hyperphagia, and weight gain) has been based on site-specific clinic-based samples. The goal of this study was to delineate the epidemiology of reversed symptoms in a large community sample and to use other symptom patterns for comparison. Method: Interviewers assessed 8,116 subjects across Ontario, aged 15‐64 years, by using the World Health Organization Composite International Diagnostic Interview. Indi...
67 Citations Source Cite
Published on Sep 1, 1995in CNS Drugs 4.21
Siegfried Kasper76
Estimated H-index: 76
(University of Vienna),
M. Stamenkovic17
Estimated H-index: 17
(University of Vienna),
Gabriele Fischer32
Estimated H-index: 32
(University of Vienna)
Summary Recurrent brief depression (RBD) fulfils DSM-IV criteria for major depres­ sion, with the exception of the duration of the depressive episodes. Recent epi­ demiological studies have confirmed the existence of RBD and estimated that it has a high prevalence in the general population and in general practice (approxi­ mately 10%). These studies also indicate a high comorbidity of RBD with attempted suicide, other forms of depression, anxiety disorders and substance abuse.
41 Citations Source Cite
Published on Jun 1, 1979in International Journal of Mental Health
Edwin W. Hoeper4
Estimated H-index: 4
Greg R. Nycz1
Estimated H-index: 1
+ 2 AuthorsIrving D. Goldberg17
Estimated H-index: 17
The prevalence of mental disorder in primary -care practice has been estimated to be between 15% and 50% (Anderson, Francis, Lion, & Daughety, 1977; Finn & Huston, 1966; Gardner, 1970; Goldberg, Kay, & Thompson, 1976; Locke & Gardner, 1969; Patrick, Eagle, & Coleman, 1978; Shepherd, Cooper, Brown, & К alt on, 1966). These estimates have been based on general practitioners T diagnoses (Finn & Huston, 1966; Goldberg, Kay, & Thompson, 1976; Locke & Gardner, 1969) or on levels of self -reported ment...
208 Citations Source Cite
Published on Apr 1, 1982in American Journal of Psychiatry 13.40
Martin B. Keller113
Estimated H-index: 113
Robert W. Shapiro13
Estimated H-index: 13
Although ‘ ‘double depression ‘ ‘-major depressive disorder superimposed on an underlying chronic depression-is a f requent phenomenon, the concept has not been well formulated clinically and has rarely been described in the research literature. The authors found that 1) 26% of 101 patients who met the criteria for major depressive disorder had an underlying chronic depressive disorder of at least 2 years’ duration, 2) “recovery” ratesfor patients with superimposed depression differed greatly de...
275 Citations Source Cite
Published on Jan 1, 1995in American Journal of Psychiatry 13.40
Cathy D. Sherbourne68
Estimated H-index: 68
Kenneth B. Wells83
Estimated H-index: 83
+ 3 AuthorsLewis L. Judd52
Estimated H-index: 52
Objective: The authors examined the clinicalsignificance ofdepressive symptoms below the threshold for depressive disorder in outpatient samples. Method: The subjects were 775 adult patients with current depressive disorder, 1,420 patients with subthreshold depression, and 1,767 hypertensive patients with and without depression, all ofwhom were visiting the offices of mental health specialists and general medical care providers in three U.S. cities. Data on demographic characteristics, severity ...
170 Citations Source Cite
Jules Angst77
Estimated H-index: 77
(University of Zurich),
A. Dobler-Mikola2
Estimated H-index: 2
(University of Zurich)
A prospective study of depressive syndromes and diagnoses was performed among a young adult Swiss population with three interviews over 7 years. Different definitions of depressive states were used: on the one hand, depressive syndromes including mood disturbances of any severity, on the other, well-defined diagnoses of depression. Women were consistently overrepresented among subjects with depressive syndromes of some length and among those with DSM-III major depressive disorder. Both sexes app...
379 Citations Source Cite
Published on Aug 1, 1997in Journal of Affective Disorders 3.79
Jules Angst77
Estimated H-index: 77
(University of Zurich),
Kathleen R. Merikangas100
Estimated H-index: 100
(Yale University)
Abstract The spectrum of depression is much wider than that reflected in the current diagnostic nomenclature. A large proportion of subjects with depression both in treatment and in the community fail to meet diagnostic criteria for either major depressive disorder (MDD) or dysthymia. Inclusion of subthreshold categories of depression dramatically improves the coverage of treated depression, particularly in community samples, and better enables the characterization of its longitudinal course. Th...
235 Citations Source Cite
Published on Oct 1, 1993in Archives of General Psychiatry
Johan Ormel103
Estimated H-index: 103
Tineke Oldehinkel4
Estimated H-index: 4
+ 1 AuthorsW. van den Brink73
Estimated H-index: 73
Background: We evaluated the long-term outcome of depression and anxiety and associated disability among primary-care attenders with common psychiatric disorders and symptoms (n=201) using binary and multicategorical, interview-based outcome measures of psychiatric illness and disability. Methods: A two-stage design was used. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness with the General Health Questionnaire and by their physician...
180 Citations Source Cite
Cited By119
Published on Nov 1, 2007in The Canadian Journal of Psychiatry
Jennifer Bethell13
Estimated H-index: 13
Anne E. Rhodes21
Estimated H-index: 21
Objective: To determine whether, and to what extent, those who reported suicidal ideation and (or) attempts in the previous year, without meeting the criteria for major depressive episode (MDE), might still have experienced subthreshold depression. Method: Data from the Canadian Community Health Survey: Mental Health and Well-Being (CCHS 1.2) were examined to estimate and compare the prevalence of depressed mood, a core symptom of MDE and subthreshold depression, within the previous month for th...
6 Citations Source Cite
Published on Sep 1, 2012in Psychiatria Danubina 1.34
Deepti M. Lobo1
Estimated H-index: 1
Mark Agius12
Estimated H-index: 12
5 Citations
Published on Jul 1, 2006in Nervenarzt 0.74
Kronmüller Kt1
Estimated H-index: 1
Mundt C1
Estimated H-index: 1
1 Citations Source Cite
Published on Jan 1, 2006in Revista Colombiana de Psiquiatría
Rebecca J. Syed , Alison R. Yung75
Estimated H-index: 75
Resumen en: Background: Depression is common, disabling and often has its onset in adolescents. Adolescents with depression are at high risk for persistence and rec...
Published on Apr 1, 2009in The Canadian Journal of Psychiatry
Tracy R.G. Giadstone24
Estimated H-index: 24
William R. Beardselee57
Estimated H-index: 57
Objective: To review the recent literature on the prevention of clinical diagnoses of depression in children and adolescents. Method: Several preventive intervention programs targeting depressive diagnoses in youth were reviewed. These programs based their prevention strategies on cognitive-behavioural and (or) interpersonal approaches, which have been found to be helpful in the treatment of depression. In addition, family-based prevention strategies were reviewed. Also, nonspecific risk factors...
104 Citations Source Cite
Published on Apr 1, 2003in Veterinary Research Communications 1.93
G. Sheppard1
Estimated H-index: 1
(University of Lincoln),
D.S. Mills1
Estimated H-index: 1
(University of Lincoln)
Veterinary behavioural medicine is marked by inconsistency in the naming and description of animal behavioural disorders, potentially hindering research and reducing the clinical utility of diagnoses. Sources of diagnostic inconsistency are suggested and parallels with human psychiatry are identified. This paper questions the use of categorical models as the basis for classification and reviews criticisms of categorical approaches in psychiatry. Evidence is presented to suggest an inconsistency ...
4 Citations Source Cite
Published on May 1, 2009in Nervenarzt 0.74
Hegerl U1
Estimated H-index: 1
Schönknecht P1
Estimated H-index: 1
Minor depression, subsyndromal depression and subthreshold depression are frequent conditions in primary care which do not fulfil the criteria of a depressive disorder but are associated with functional disability, impairment of quality of life, and health care use. This paper reviews studies on the clinical evidence of pharmacotherapy, psychotherapy, and interventions to improve primary care. In this regard, whether clinical relevance of antidepressant therapies can be concluded from difference...
12 Citations Source Cite
Daniela Victor8
Estimated H-index: 8
Matthias Backenstrass17
Estimated H-index: 17
+ 3 AuthorsKlaus-Thomas Kronmüller13
Estimated H-index: 13
Zusammenfassung: Nachdem der depressiven Personlichkeitsstorung lange Zeit nur eine historische Bedeutung zukam, gewann sie in letzter Zeit im Zusammenhang mit der Differenzierung leichterer und chronisch verlaufender Formen der Depression wieder an Bedeutung. Dies druckt sich auch in der Aufnahme des Konzeptes in die Forschungskriterien des DSM-IV aus. Zu den Hauptmerkmalen der depressiven Personlichkeitsstorung zahlen negative, pessimistische Vorstellungen uber die eigene Person und andere Men...
Source Cite
Published on Oct 1, 2002in Psychiatry and Clinical Neurosciences 3.20
Franco Benazzi42
Estimated H-index: 42
(University of California, San Diego)
Depressive mixed state (DMX), a major depressive episode (MDE) combined with few manic/hypomanic symptoms, is understudied. Age and gender are important variables in mood disorders. The aim of the present study was to determine whether age and gender had any effect on the frequency of DMX. Consecutive unipolar (n = 144) and bipolar II (n = 218) drug-free MDE out-patients were interviewed with the Structured Clinical Interview for DSM-IV when presenting for MDE treatment. The presence of hypomani...
19 Citations Source Cite
Published on Jan 1, 2002in Revista De Psiquiatria Clinica
Michael Bauer69
Estimated H-index: 69
Peter C. Whybrow39
Estimated H-index: 39
+ 2 AuthorsH.-J. Möller97
Estimated H-index: 97
These practice guidelines for the biological treatment of unipolar depressive disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal for developing these guidelines was to systematically review all available evidence pertaining to the treatment of the complete spectrum of unipolar depressive disorders, and to produce a series of practice recommendations that are clinically and scientifically meaningful based on the ...
101 Citations Source Cite