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Depressive spectrum diagnoses

Published on Mar 1, 2000in Comprehensive Psychiatry 2.59
· DOI :10.1016/S0010-440X(00)80007-3
Jules Angst81
Estimated H-index: 81
,
Robert Sellar1
Estimated H-index: 1
,
Kathleen R. Merikangas102
Estimated H-index: 102
Cite
Abstract
There has been widespread debate about the validity of the contemporary diagnostic classification system of depression. The major goal of this study is to examine the prognostic significance of each of the major subtypes of depression using data from 5 interviews of a 15-year prospective community-based cohort study. The stability of the following diagnostic subtypes across the duration of the study was examined: major depressive disorder (MDD), dysthymia, recurrent brief depression (RBD), and minor depression. The results show that there was little stability for the specific subtypes of depression among those who continued to manifest depression during the follow-up period; 51% of those with MDD and 44% of those with RBD met criteria for another subtype of depression. When stability was observed, the same subtype often occurred in combination with the development of another subtype. Among individuals with a single subtype, severity was greatest among those with dysthymia, whereas individuals with combined subtypes had greater severity than those with a single subtype. The lack of longitudinal stability of the diagnostic subtypes of depression suggests that depression is better expressed as a spectrum rather than a set of discrete subtypes.
  • References (38)
  • Citations (118)
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References38
Newest
Published on Aug 1, 1998in Archives of General Psychiatry
Lewis L. Judd52
Estimated H-index: 52
,
Hagop S. Akiskal96
Estimated H-index: 96
+ 9 AuthorsTimothy I. Mueller43
Estimated H-index: 43
9 of 10 patients spent weeks at 3 or 4 different levels during follow-up. The MinD (27%) and SSD (17%) symptom levels were more common than the MDD (15%) symptom level. Patients with double depression and recurrent depression had more chronic symptoms than patients with their first lifetime major depressive episode (72% and 65%, respectively, vs 46% of follow-up weeks). Conclusion: The long-term weekly course of unipolar MDD is dominated by prolonged symptomatic chronicity. Combined MinD and SSD...
613 Citations Source Cite
Published on Feb 1, 1998in American Journal of Psychiatry 13.65
Kenneth S. Kendler152
Estimated H-index: 152
(MCV: VCU Medical Center),
Charles O. Gardner42
Estimated H-index: 42
OBJECTIVE: Little is known about the boundaries between major depression and milder subsyndromal depressive states. With respect to depressive symptoms, does DSM-IV “carve nature at its joints”? METHOD: In personally interviewed female twins from a population-based registry, the authors examined whether a range of values along three dimensions of the depressive syndrome assessed in the last year (number of symptoms listed in DSM-III-R under diagnostic criterion A for major depressive episode, le...
302 Citations Source Cite
Published on Oct 1, 1997in Archives of General Psychiatry
Frederic M. Quitkin63
Estimated H-index: 63
,
Jonathan W. Stewart59
Estimated H-index: 59
+ 2 AuthorsDonald F. Klein85
Estimated H-index: 85
Since Aubrey Lewis' classic study there has been debate about whether the distinction between depressive subtypes is categorical or dimensional. 1-6 A recent article by Kendler et al 7 supports a categorical classification of depressive subtypes. Using a different means of validating nosological distinctions, our group reached similar conclusions and we think it relevant to review the similarities and differences between our findings and those of Kendler et al. In a prospective epidemiological s...
15 Citations Source Cite
Published on Aug 1, 1997in Journal of Affective Disorders 4.08
Ronald C. Kessler229
Estimated H-index: 229
(UM: University of Michigan),
Shanyang Zhao24
Estimated H-index: 24
(UM: University of Michigan)
+ 1 AuthorsMarvin Swart74
Estimated H-index: 74
(Duke University)
Abstract Data from the National Comorbidity Survey are used to study the lifetime prevalences, correlates, course and impairments associated with minor depression (mD), major depression with 5–6 symptoms (MD 5–6), and major depression with seven or more symptoms (MD 7–9) in an effort to determine whether mD is on a continuum with MD. There is a monotonic increase in average number of episodes, average length of longest episode, impairment, comorbidity, and parental history of psychiatric disorde...
574 Citations Source Cite
Published on Aug 1, 1997in Journal of Affective Disorders 4.08
Martin B. Keller116
Estimated H-index: 116
(Brown University),
Robert M. A. Hirschfeld72
Estimated H-index: 72
(UTMB: University of Texas Medical Branch),
Hanks Dl4
Estimated H-index: 4
(Brown University)
Abstract Whether depression is a single disease that varies from mild to severe, with varying episode durations and difficult course patterns, or whether it is an umbrella diagnosis representing depressive subtypes with different psychological and biological characteristics has been debated by clinicians and researchers for many years. However, most scientists now agree that understanding the heterogeneous subtypes of depression allows for greater accuracy in describing and differentiating patie...
52 Citations Source Cite
Published on Aug 1, 1997in Journal of Affective Disorders 4.08
Wolfgang Maier101
Estimated H-index: 101
(University of Bonn),
Michael Gänsicke11
Estimated H-index: 11
(University of Bonn),
Olaf Weiffenbach6
Estimated H-index: 6
(University of Bonn)
Abstract Recent epidemiological research in the general population and primary care demonstrated that a substantial proportion of disabling depressive syndromes do not meet the diagnostic criteria for major depression. This observation proposes less restrictive diagnostic definitions of depression. However, a gain in sensitivity may induce a substantial loss of specificity. A variety of diagnostic definitions of subthreshold depression has been proposed balancing both aspects. However, the less ...
74 Citations Source Cite
Published on Aug 1, 1997in Journal of Affective Disorders 4.08
Jules Angst81
Estimated H-index: 81
(UZH: University of Zurich),
Kathleen R. Merikangas102
Estimated H-index: 102
(Yale University)
Abstract The spectrum of depression is much wider than that reflected in the current diagnostic nomenclature. A large proportion of subjects with depression both in treatment and in the community fail to meet diagnostic criteria for either major depressive disorder (MDD) or dysthymia. Inclusion of subthreshold categories of depression dramatically improves the coverage of treated depression, particularly in community samples, and better enables the characterization of its longitudinal course. Th...
236 Citations Source Cite
Published on Jul 1, 1997in American Journal of Psychiatry 13.65
Robert D. Levitan43
Estimated H-index: 43
,
Alain Lesage41
Estimated H-index: 41
+ 2 AuthorsSidney H. Kennedy52
Estimated H-index: 52
Objective: Most research on depression with reversed neurovegetative features (hypersomnia, hyperphagia, and weight gain) has been based on site-specific clinic-based samples. The goal of this study was to delineate the epidemiology of reversed symptoms in a large community sample and to use other symptom patterns for comparison. Method: Interviewers assessed 8,116 subjects across Ontario, aged 15‐64 years, by using the World Health Organization Composite International Diagnostic Interview. Indi...
68 Citations Source Cite
Published on Feb 1, 1997in Journal of Affective Disorders 4.08
Shauna K. Donaldson5
Estimated H-index: 5
(SBU: Stony Brook University),
Daniel N. Klein72
Estimated H-index: 72
(SBU: Stony Brook University)
+ 1 AuthorsJoseph E. Schwartz91
Estimated H-index: 91
(SBU: Stony Brook University)
Abstract There is an extremely high rate of comorbidity between Dysthymic Disorder (DD) and Major Depressive Disorder (MDD). We used family study data to test four competing models of the relationship between DD, MDD, and comorbid DD/MDD: (1) DD, MDD, and DD/MDD are all variants of a single condition; (2) MDD and DD/MDD are similar, but differ from DD; (3) DD and DD/MDD are similar, but differ from MDD; and (4) all three conditions are distinct disorders. Subjects were the first-degree relatives...
27 Citations Source Cite
Published on Jan 1, 1997in American Journal of Psychiatry 13.65
Jonathan W. Stewart59
Estimated H-index: 59
,
Elaine Tricamo24
Estimated H-index: 24
+ 1 AuthorsFrederic M. Quitkin63
Estimated H-index: 63
Objective: Demonstration of antidepressant efficacy beyond 6 months has infrequently been addressed, and no long-term efficacy data exist for patients with chronic atypical depression. Method: Sixty patients with atypical depression (according to Columbia University criteria) of at least 2 years’ duration and who had improved with imipramine or phenelzine were stabilized for 6 months and then randomly continued the same medication or placebo for 6 months. Results: Several baseline differences su...
51 Citations Source Cite
Cited By118
Newest
Published on Jun 1, 2019in Psychological Medicine 5.64
Selina Wolke2
Estimated H-index: 2
,
Mitul A. Mehta44
Estimated H-index: 44
+ 8 AuthorsEllen Leibenluft72
Estimated H-index: 72
Background Aberrations in reward and penalty processing are implicated in depression and putatively reflect altered dopamine signalling. This study exploits the advantages of a placebo-controlled design to examine how a novel D 2 antagonist with adjunctive antidepressant properties modifies activity in the brain's reward network in depression. Methods We recruited 43 medication-naive subjects across the range of depression severity (Beck's Depression Inventory-II score range: 0–43), including he...
1 Citations Source Cite
Published on May 21, 2019in Emerging adulthood
Audrey Wittrup2
Estimated H-index: 2
(UVA: University of Virginia),
Noelle M. Hurd16
Estimated H-index: 16
(UVA: University of Virginia)
Source Cite
Published on Dec 1, 2018in Journal of Affective Disorders 4.08
Marlous Tuithof10
Estimated H-index: 10
,
M. ten Have49
Estimated H-index: 49
+ 3 AuthorsR. de Graaf83
Estimated H-index: 83
Abstract Background Information on the natural course of subthreshold depression and risk factors for the development of a full-blown depressive disorder in the general population is scarce. This information is crucial to understand the development of depression and to advance indicated depression prevention. Methods Using longitudinal data from a representative population-based study (the Netherlands Mental Health Survey and Incidence Study-2) we assessed 3-year course of subthreshold depressio...
Source Cite
Published on Dec 1, 2018in BMC Psychiatry 2.67
Sumaya Mall11
Estimated H-index: 11
(UCT: University of Cape Town),
Philippe Mortier10
Estimated H-index: 10
(Katholieke Universiteit Leuven)
+ 3 AuthorsChristine Lochner33
Estimated H-index: 33
(Stellenbosch University)
College students are at risk of depression. This risk may be increased by the experience of childhood adversity and/or recent stressors. This study examined the association between reported experiences of childhood adversity, recent stressors and depression during the last 12 months in a cohort of South African university students. Six hundred and eighty-six first year students at Stellenbosch University in South Africa completed a health-focused e-survey that included items on childhood adversi...
2 Citations Source Cite
Published on Jun 1, 2018in Social Psychiatry and Psychiatric Epidemiology 3.15
Yuying Sun2
Estimated H-index: 2
(HKU: University of Hong Kong),
Jette Möller19
Estimated H-index: 19
(KI: Karolinska Institutet)
+ 3 AuthorsYvonne Forsell42
Estimated H-index: 42
(KI: Karolinska Institutet)
Purpose To identify how severity of depression predicts future utilization of psychiatric care and antidepressants.
2 Citations Source Cite
Anna Weinberg26
Estimated H-index: 26
(McGill University),
Aislinn Sandre1
Estimated H-index: 1
(McGill University)
Abstract Background Abnormal patterns of attention to threat and reward have been proposed as potential mechanisms of dysfunction in anxiety and mood disorders. However, research on this topic has been inconsistent, perhaps because of both clinical heterogeneity in the samples assessed and measurement of attentional biases that is temporally imprecise. Methods The present study measured transdiagnostic symptoms of anxiety and depression in 205 young adults and recorded affect-modulated event-rel...
4 Citations Source Cite
Published on Sep 14, 2017in Mental Health, Religion & Culture
Cristina Cabras2
Estimated H-index: 2
,
Giorgia Loi1
Estimated H-index: 1
+ 1 AuthorsMarina Mondo2
Estimated H-index: 2
1 Citations Source Cite
Published on Apr 1, 2017in Psychiatry Research-neuroimaging 2.21
Caroline L. Vandeleur17
Estimated H-index: 17
(CHUV: University Hospital of Lausanne),
S. Fassassi3
Estimated H-index: 3
(CHUV: University Hospital of Lausanne)
+ 9 AuthorsJean-Michel Aubry34
Estimated H-index: 34
Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders (PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied the DSM-5 criteria throughout the range of depressive disorders. The aims of the present study were to 1) establish the lifetime prevalence of specific depressive disorders according to the new DSM-5 definitions in a community sample, and 2) determine their clinical relevance in terms of socio-demographic characteristics, co...
17 Citations Source Cite
Published on Mar 1, 2017in Addiction 6.85
Amanda R. Mathew10
Estimated H-index: 10
(NU: Northwestern University),
Lee Hogarth27
Estimated H-index: 27
(University of Exeter)
+ 2 AuthorsBrian Hitsman24
Estimated H-index: 24
(NU: Northwestern University)
Background and aims Despite decades of research on co-occurring smoking and depression, cessation rates remain consistently lower for depressed smokers than for smokers in the general population, highlighting the need for theory-driven models of smoking and depression. This paper provides a systematic review with a particular focus on psychological states that disproportionately motivate smoking in depression, and frame an incentive learning theory account of smoking-depression co-occurrence. Me...
39 Citations Source Cite
Hyun Woo Park1
Estimated H-index: 1
(SCH: Soonchunhyang University),
Young Hwangbo16
Estimated H-index: 16
(SCH: Soonchunhyang University)
+ 2 AuthorsWook Han2
Estimated H-index: 2
(SCH: Soonchunhyang University)
Background The present study investigated the prevalence of depressive symptoms in older Koreans and identified associations between depressive symptoms and occupational factors.
2 Citations Source Cite