A novel glucose biosensor based on the immobilization of glucose oxidase on layer-by-layer assembly film of copper phthalocyanine functionalized graphene

A negatively charged glassy carbon electrode (GCE) was formed through the electrochemical modification of sulfanilic acid (ABS). Subsequently, graphene composites functionalized with copper phthalocyanine-3,4′,4″,4‴-tetrasulfonic acid tetrasodium salt (TSCuPc) or alcian blue pyridine variant (AB) were assembled layer-by-layer (LbL) via alternate electrostatic adsorption onto the ABS/GCE surface to obtain a uniform and stable graphene multilayer...