Modulation of natural killer cell-mediated cytotoxicity by tamoxifen and estradiol
Abstract
Background. The nonsteroidal antiestrogenic drug, tamoxifen, inhibits the growth of estrogen receptor-positive tumors by interfering with the growth-stimulatory effect of estradiol. However, there is compelling evidence that tamoxifen treatment also is beneficial for patients with estrogen receptor-negative tumors. The hypothesis that tamoxifen is capable of enhancing the immunologic defense of tumor-bearing hosts was been investigated as a...
Paper Details
Title
Modulation of natural killer cell-mediated cytotoxicity by tamoxifen and estradiol
Published Date
Jan 15, 1995
Journal
Volume
75
Issue
2
Pages
591 - 599
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Notes
History