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The HOX Gene Cluster in the Bivalve Mollusc Mytilus galloprovincialis

Published on Aug 1, 2005in Biochemical Genetics1.931
· DOI :10.1007/s10528-005-6780-4
M. Luz Pérez-Parallé9
Estimated H-index: 9
(University of Santiago de Compostela),
Pablo Carpintero8
Estimated H-index: 8
(University of Santiago de Compostela)
+ 2 AuthorsJosé L. Sánchez8
Estimated H-index: 8
(University of Santiago de Compostela)
Abstract
The clustered Hox genes play a central role in the regulation of development in bilaterian animals. In this study, we analyzed the homeobox-containing genes in a bivalve mollusc, the mussel Mytilus galloprovincialis, an unsegmented spiralian lophotrochozoan. We isolated and characterized four Hox cluster genes using the polymerase chain reaction with specific primers. Molecular alignments and phylogenetic analysis indicate that these mussel genes are homologs of the anterior group (pb ortholog), paralog group 3, and central group (PG4/Dfd and PG5/Scr) genes. The putative homeodomain sequences were designated Mgox1, Mgox2, Mgox3, and Mgox4.
  • References (25)
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References25
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We report the spatial expression patterns of five anterior Hox genes during larval development of the gastropod mollusc Haliotis asinina, an unsegmented spiralian lophotrochozoan. Molecular alignments and phylogenetic analysis indicate that these genes are homologues of Drosophila HOM-C genes labial, proboscipedia, zen, Deformed, and Sex combs reduced; the abalone genes are named Has-Hox1, -Hox2, -Hox3, -Hox4, and -Hox5. Has-Hox transcripts are first detected in the free-swimming trochophore lar...
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