Review paper
Toward Simplifying and Accurately Formulating Fragment Assembly
Abstract
The fragment assembly problem is that of reconstructing a DNA sequence from a collection of randomly sampled fragments. Traditionally, the objective of this problem has been to produce the shortest string that contains all the fragments as substrings, but in the case of repetitive target sequences this objective produces answers that are overcompressed. In this paper, the problem is reformulated as one of finding a maximum-likelihood...
Paper Details
Title
Toward Simplifying and Accurately Formulating Fragment Assembly
Published Date
Jan 1, 1995
Volume
2
Issue
2
Pages
275 - 290
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