Brain atrophy over time in genetic and sporadic frontotemporal dementia: a study of 198 serial magnetic resonance images

Background and purpose The aim of our study was to determine the utility of longitudinal magnetic resonance imaging ( MRI ) measurements as potential biomarkers in the main genetic variants of frontotemporal dementia ( FTD ), including microtubule‐associated protein tau ( MAPT ) and progranulin ( GRN ) mutations and C9 ORF 72 repeat expansions, as well as sporadic FTD . Methods In this longitudinal study, 58 subjects were identified who had at...