Extracellular superoxide dismutase and cardiovascular disease
Abstract
Excessive production and/or inadequate removal of reactive oxygen species, especially superoxide anion (O(2)(*-)), have been implicated in the pathogenesis of many cardiovascular diseases, including atherosclerosis, hypertension, diabetes, and in endothelial dysfunction by decreasing nitric oxide (NO) bioactivity. Since the vascular levels of O(2)(*-) are regulated by the superoxide dismutase (SOD) enzymes, a role of SOD in the cardiovascular...
Paper Details
Title
Extracellular superoxide dismutase and cardiovascular disease
Published Date
Aug 1, 2002
Journal
Volume
55
Issue
2
Pages
239 - 249
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