Lecithin as a Therapeutic Agent in Ulcerative Colitis
Abstract
Lecithin [phosphatidylcholine (PC)] was shown to account for more than 70% of total phospholipids within the intestinal mucus layer. It is arranged in lamellar membranes (surfactant-like particles) and establishes a hydrophobic barrier preventing invasion of the colonic commensal microbiota. In ulcerative colitis (UC), the mucus PC content was demonstrated to be reduced by about 70%, irrespective of the presence of inflammation. This may be of...
Paper Details
Title
Lecithin as a Therapeutic Agent in Ulcerative Colitis
Published Date
Jan 1, 2013
Journal
Volume
31
Issue
3-4
Pages
388 - 390
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