Increased uptake of non‐pathogenic E. coli via the follicle‐associated epithelium in longstanding ileal Crohn's disease

In Crohn's disease (CD), inflammation is driven by luminal commensal micro‐organisms; however, mechanisms of early phases of inflammation need further clarification. The earliest observable lesions of recurrent CD are microscopic erosions at the specialized follicle‐associated epithelium (FAE), which lines the Peyer's patches. Therefore, our aim was to investigate the mucosal barrier to non‐pathogenic bacteria in FAE of CD. The FAE of...