Comparison of IgE Antibody Concentrations to Pyromellitic Dianhydride-Modified Laminin and Human Serum Albumin in Sera of Exposed Workers with Respiratory Complaints

Acid anhydrides are used in a variety of industrial branches because of their highly reactive anhydride groups. Adverse effects of anhydride exposure include toxic/irritative effects as well as IgE- and IgG-mediated respiratory disorders. It was the aim of this study to examine the usefulness of conjugates of pyromellitic dianhydride (PMDA) and laminin, a respiratory tract protein, for the in vitro diagnosis of sensitization to PMDA.Sera of...