Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms.

Volume: 15, Issue: 3, Pages: 349 - 362
Published: Sep 1, 1991
Abstract
Exposure to high doses of organophosphorus nerve agents such as soman, even with carbamate pretreatment, produces a variety of toxic cholinergic signs, including secretions, convulsions and death. Evidence suggests that soman-induced convulsions may be associated with postexposure brain neuropathology. The purpose of this study was to investigate the pharmacologic mechanism of action of soman-induced convulsions and of anticonvulsant drugs....
Paper Details
Title
Anticonvulsants for poisoning by the organophosphorus compound soman: pharmacological mechanisms.
Published Date
Sep 1, 1991
Volume
15
Issue
3
Pages
349 - 362
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