Long-Term Effect of Weight Loss on Obstructive Sleep Apnea Severity in Obese Patients with Type 2 Diabetes

To examine whether the initial benefit of weight loss on obstructive sleep apnea (OSA) severity at 1 year is maintained at 4 years. Randomized controlled trial with follow-up at 1, 2, and 4 years. 4 Look AHEAD clinical centers. Two hundred sixty-four obese adults with type 2 diabetes and OSA. Intensive lifestyle intervention with a behavioral weight loss program or diabetes support and education. Change in apnea-hypopnea index on polysomnogram....