Body composition and weight reduction in relation to antigen and activity of plasminogen activitor inhibitor (PAI-1) in overweight individuals

Tissue plasminogen activator inhibitor type 1 (PAI-1) plasma activity and antigen levels were determined in 22 healthy overweight individuals (11 females and 11 males), before and after a period of 13 weeks during which the participants were subjected to a 4.2 MJ deficient diet. The diet intervention resulted in a significant reduction in anthropometric variables under study (P<0.005). PAI-1 activity and antigen decreased significantly in both...