Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies.
Abstract
Outbred laboratory mouse populations are widely used in biomedical research. Since little is known about the degree of genetic variation present in these populations, they are not widely used for genetic studies. Commercially available outbred CD-1 mice are drawn from an extremely large breeding population that has accumulated many recombination events, which is desirable for genome-wide association studies. We therefore examined the degree of...
Paper Details
Title
Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies.
Published Date
Mar 6, 2009
Journal
Volume
4
Issue
3
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