Affinity separation and enrichment methods in proteomic analysis
Abstract
Protein separation or enrichment is one of the rate-limiting steps in proteomic studies. Specific capture and removal of highly-abundant proteins (HAP) with large sample-handling capacities are in great demand for enabling detection and analysis of low-abundant proteins (LAP). How to grasp and enrich these specific proteins or LAP in complex protein mixtures is also an outstanding challenge for biomarker discovery and validation. In response to...
Paper Details
Title
Affinity separation and enrichment methods in proteomic analysis
Published Date
Aug 1, 2008
Journal
Volume
71
Issue
3
Pages
284 - 303
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