Recent developments in ruthenium anticancer drugs
Abstract
Interest in Ru anticancer drugs has been growing rapidly since NAMI-A ((ImH(+))[Ru(III)Cl(4)(Im)(S-dmso)], where Im = imidazole and S-dmso = S-bound dimethylsulfoxide) or KP1019 ((IndH(+))[Ru(III)Cl(4)(Ind)(2)], where Ind = indazole) have successfully completed phase I clinical trials and an array of other Ru complexes have shown promise for future development. Herein, the recent literature is reviewed critically to ascertain likely mechanisms...
Paper Details
Title
Recent developments in ruthenium anticancer drugs
Published Date
Jan 1, 2009
Journal
Volume
1
Issue
6
Pages
458 - 458
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Notes
History