Metals and DNA: Molecular Left-Handed Complements
Abstract
Chiral metal complexes provide unique molecular probes for DNA. Chiral reagents that "recognize" different local structures along the DNA strand have been designed by a process in which the asymmetry in shape and size of the complex is matched to that of the DNA helical groove. As a result, the chiral metal complexes provide very sensitive probes for local helical structure, both left- and right-handed. Direct coordination of chiral complexes to...
Paper Details
Title
Metals and DNA: Molecular Left-Handed Complements
Published Date
Aug 15, 1986
Journal
Volume
233
Issue
4765
Pages
727 - 734
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