Diffusion Tensor Imaging Study of the Response to Constraint-Induced Movement Therapy of Children With Hemiparetic Cerebral Palsy and Adults With Chronic Stroke

Objective To investigate the relationship of white matter integrity and path of the corticospinal tract (CST) on arm function before and after constraint-induced (CI) movement therapy in children with hemiparetic cerebral palsy (CP) and adults with chronic stroke. Design Study 1 used a multiple-baseline pre-post design. Study 2 was a randomized controlled trial. Setting Outpatient rehabilitation laboratory. Participants Study 1 included children...