Regulation of the G2/M transition by p53.

Volume: 20, Issue: 15, Pages: 1803 - 1815
Published: Apr 5, 2001
Abstract
p53 protects mammals from neoplasia by inducing apoptosis, DNA repair and cell cycle arrest in response to a variety of stresses. p53-dependent arrest of cells in the G1 phase of the cell cycle is an important component of the cellular response to stress. Here we review recent evidence that implicates p53 in controlling entry into mitosis when cells enter G2 with damaged DNA or when they are arrested in S phase due to depletion of the substrates...
Paper Details
Title
Regulation of the G2/M transition by p53.
Published Date
Apr 5, 2001
Journal
Volume
20
Issue
15
Pages
1803 - 1815
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.