Original paper

Novel gallium(III) complexes containing phthaloyl derivatives of neutral aminoacids with apoptotic activity in cancer cells

Volume: 694, Issue: 14, Pages: 2191 - 2197
Published: Jun 1, 2009
Abstract
The reaction of N-phthaloylglycine and N-phthaloyl-dl-alanine with trimethylgallium (1:1) yielded the dinuclear complexes [Me2Ga(μ-O2CCH2N(CO)2C6H4)]2 (1) and RS-[Me2Ga(μ-O2CCHMeN(CO)2C6H4)]2 (2), respectively. The molecular structure of 2 was determined by X-ray diffraction studies. The cytotoxic activity of the organogallium(III) complexes (1 and 2) was tested against human tumour cell lines 8505C anaplastic thyroid cancer, A253 head and neck...
Paper Details
Title
Novel gallium(III) complexes containing phthaloyl derivatives of neutral aminoacids with apoptotic activity in cancer cells
Published Date
Jun 1, 2009
Volume
694
Issue
14
Pages
2191 - 2197
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