Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli

Volume: 40, Issue: 12, Pages: 5569 - 5576
Published: Jul 1, 2012
Abstract
The clustered regularly interspaced short palindromic repeats and their associated proteins (CRISPR/Cas) constitute a recently identified prokaryotic defense mechanism against invading nucleic acids. Activity of the CRISPR/Cas system comprises of three steps: (i) insertion of alien DNA sequences into the CRISPR array to prevent future attacks, in a process called ‘adaptation’, (ii) expression of the relevant proteins, as well as expression and...
Paper Details
Title
Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli
Published Date
Jul 1, 2012
Volume
40
Issue
12
Pages
5569 - 5576
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