Overweight Humans Are Resistant to the Weight-Reducing Effects of Melanocortin4–10

Volume: 91, Issue: 2, Pages: 522 - 525
Published: Feb 1, 2006
Abstract
By enhancing energy expenditure and suppressing appetite, melanocortin peptides derived from proopiomelanocortin play a primary role in the hypothalamic regulation of body weight. In a recent study in normal-weight adults, the 6-wk intranasal administration of the MSH/ACTH(4-10) core fragment of proopiomelanocortin resulted in a distinct reduction of body weight and body fat, accompanied by significant decreases in leptin and insulin plasma...
Paper Details
Title
Overweight Humans Are Resistant to the Weight-Reducing Effects of Melanocortin4–10
Published Date
Feb 1, 2006
Volume
91
Issue
2
Pages
522 - 525
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