Original paper
TCEP-based rSDS–PAGE AND nLC–ESI-LTQ-MS/MS for oxaliplatin metalloproteomic analysis
Abstract
In this work, the reactivity of the citostatic drugs such as oxaliplatin, cisplatin and carboplatin towards proteins and the stability of Pt–protein complexes along their storage were evaluated. Neither native-PAGE nor nrSDS–PAGE seems to be suitable for the separation of carboplatin-binding proteins. A reducing electrophoretic separation procedure able to maintain the integrity of oxaliplatin–protein complexes has been developed. The method is...
Paper Details
Title
TCEP-based rSDS–PAGE AND nLC–ESI-LTQ-MS/MS for oxaliplatin metalloproteomic analysis
Published Date
Nov 1, 2013
Journal
Volume
116
Pages
581 - 592
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History