The Correct Phylogenetic Relationship of KdsA (3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase) with One of Two Independently Evolved Classes of AroA (3-Deoxy-D-arabino-heptulosonate 7-Phosphate Synthase)

-manno-octulosonate8-phosphate (KDOP) synthases.DAHP is the initial product that is specifically com-mitted to the biosynthesis of aromatic amino acids and avariety of other aromatic compounds via the action ofDAHP synthase. KDOP is best known as a key precursorof lipopolysaccharide in gram-negative bacteria, but itswider distribution in capsular polysaccharides, lipogly-can of Chlorella, and cell walls of higher plants impliesother functional...