The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion

Volume: 133, Issue: 2, Pages: 230 - 255
Published: Feb 1, 2012
Abstract
Myocardial ischemia-reperfusion injury is an important cause of impaired heart function in the early postoperative period subsequent to cardiac surgery. Reactive oxygen species (ROS) generation increases during both ischemia and reperfusion and it plays a central role in the pathophysiology of intraoperative myocardial injury. Unfortunately, the cellular source of these ROS during ischemia and reperfusion is often poorly defined. Similarly,...
Paper Details
Title
The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion
Published Date
Feb 1, 2012
Volume
133
Issue
2
Pages
230 - 255
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