Intracellular Effects of Nitric Oxide on Force Production and Ca2+Sensitivity of Cardiac Myofilaments
Abstract
The gaseous free radical nitric oxide (NO*) has been implicated in a wide range of physiological functions and also has a role in the pathogenesis of cellular injury. It has been suggested that NO* and its congeners may exert effects on actin-myosin crossbridge cycling by modulating critical thiols on the myosin head. To understand the mode and site of actin of NO* in myofibrils, the effects of the NO* donor...
Paper Details
Title
Intracellular Effects of Nitric Oxide on Force Production and Ca2+Sensitivity of Cardiac Myofilaments
Published Date
Dec 1, 1999
Volume
1
Issue
4
Pages
509 - 521
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