Immune mechanisms in medium and large-vessel vasculitis
Abstract
Vasculitis of the medium and large arteries, most often presenting as giant cell arteritis (GCA), is an infrequent, but potentially fatal, type of immune-mediated vascular disease. The site of the aberrant immune reaction, the mural layers of the artery, is strictly defined by vascular dendritic cells, endothelial cells, vascular smooth muscle cells and fibroblasts, which engage in an interaction with T cells and macrophages to, ultimately,...
Paper Details
Title
Immune mechanisms in medium and large-vessel vasculitis
Published Date
Dec 1, 2013
Journal
Volume
9
Issue
12
Pages
731 - 740
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Notes
History