Chemistry

Diuretic

Traditional medicine

Medicine

Pharmacology

Indian Journal of Pharmaceutical Sciences

Crude aqueous extract of Cleome rutidosperma was investigated for diuretic and antibacterial activity. The diuretic activity was tested in rats at 400 and 600 mg/kg, orally and compared with furosemide (20 mg/kg, intraperitoneally) as the standard. The antibacterial activity was assessed by disc diffusion method against Bacillus subtilis , Bacillus laterosporus , Staphylococcus aureus , Micrococcous luteus, Pseudomonas aeruginosa , Vibrio cholerae , Escherichia coli and Salmonella typhi at concentrations of 100, 200 and 400 µg/disc respectively. Ciprofloxacin (5 µg/disc) was used as reference control for the antibacterial study. The extract was found to possess significant dose dependent diuretic activity and also effective against both gram-positive and gram-negative bacteria in a concentration dependent manner.

Diuretic and antibacterial activity of aqueous extract of &lt;i&gt; Cleome rutidosperma&lt;/i&gt; D.C.

Diuretic and antibacterial activity of aqueous extract of <i> Cleome rutidosperma</i> D.C.