Snail modulates the assembly of fibronectin via α5 integrin for myocardial migration in zebrafish embryos
Abstract
The Snail family member snail encodes a zinc finger-containing transcriptional factor that is involved in heart formation. Yet, little is known about how Snail regulates heart development. Here, we identified that one of the duplicated snail genes, snai1b, was expressed in the heart region of zebrafish embryos. Depletion of Snai1b function dramatically reduced expression of α5 integrin, disrupted Fibronectin layer in the heart region, especially...
Paper Details
Title
Snail modulates the assembly of fibronectin via α5 integrin for myocardial migration in zebrafish embryos
Published Date
Mar 26, 2014
Journal
Volume
4
Issue
1
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